Description

Methyl 6-Bromoimidazo[1,2-A]Pyridine-2-Carboxylate is a high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound is critical for medicinal chemistry research and development, serving as a versatile precursor for creating novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its imidazopyridine core.
• Agrochemical Synthesis: Serves as a building block for creating new crop protection agents and pesticides.
• Chemical Biology Probes: Employed in the synthesis of tool compounds and molecular probes for biological target identification and validation.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of complex molecules under cGMP or research-grade conditions.

Basic Information

Product Name	Methyl 6-Bromoimidazo[1,2-A]Pyridine-2-Carboxylate
CAS No.	354548-08-6
Molecular Formula	C9H7BrN2O2
Molecular Weight	255.07 g/mol
Synonyms	6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid methyl ester; Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate; 6-Bromo-2-(methoxycarbonyl)imidazo[1,2-a]pyridine; Methyl 6-bromo-2-imidazo[1,2-a]pyridinecarboxylate; 354548-08-6; Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-bromo-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Bromoimidazo[1,2-A]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support development and commercial projects with material suitable for research use and can supply under more stringent quality agreements as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.