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(R)-B-Amino-4-Bromo-Benzeneethanol CAS NO 354153-64-3
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CAS No.:354153-64-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-B-Amino-4-Bromo-Benzeneethanol is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its role in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutics. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis and process development.
Application
- Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, including potential candidates for central nervous system (CNS) and cardiovascular therapies.
- Asymmetric Catalysis Research: Used as a precursor or ligand in the development of new catalytic systems for stereoselective transformations.
- Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients in advanced crop protection agents.
- Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals requiring specific stereochemistry.
- Academic & Process R&D: Utilized in research laboratories for method development and studying structure-activity relationships (SAR).
- Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.
Basic Information
| Product Name | (R)-B-Amino-4-Bromo-Benzeneethanol |
| CAS No. | 354153-64-3 |
| Molecular Formula | C8H10BrNO |
| Molecular Weight | 216.08 g/mol |
| Synonyms | (R)-2-Amino-1-(4-bromophenyl)ethanol; (R)-1-(4-Bromophenyl)-2-aminoethanol; (R)-4-Bromo-β-amino-phenethyl alcohol; (R)-p-Bromo-β-amino-phenethyl alcohol; (R)-B-Amino-4-Bromobenzeneethanol; (R)-2-Amino-2-(4-bromophenyl)ethan-1-ol; (R)-1-Amino-2-(4-bromophenyl)ethanol; (R)-4'-Bromo-2-amino-1-phenylethanol |
| EINECS | Contact for details |
Quality Control
Our (R)-B-Amino-4-Bromo-Benzeneethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Related Substances (HPLC) | Individual impurity ≤ 0.5%; Total impurities ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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