Description

3-Propanoyl-5-Bromo-Benzo[B]Thiophene is a high-purity, synthetically valuable brominated heterocyclic building block. This compound is specifically engineered for advanced organic synthesis, serving as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bioactivity of the benzothiophene core.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers due to its electron-rich thiophene ring.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and functional group transformations, facilitated by the reactive bromine substituent.
• Academic & Contract Research: Essential for methodological studies and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	3-Propanoyl-5-Bromo-Benzo[B]Thiophene
CAS No.	353487-39-5
Molecular Formula	C11H9BrOS
Molecular Weight	269.16 g/mol
Synonyms	5-Bromo-3-propionylbenzo[b]thiophene; 1-(5-Bromobenzo[b]thiophen-3-yl)propan-1-one; 3-Propionyl-5-bromobenzo[b]thiophene; 5-Bromo-3-propionyl-1-benzothiophene; 353487-39-5; 3-Propanoyl-5-bromobenzo[b]thiophene; 5-Bromobenzo[b]thiophene-3-yl ethyl ketone
EINECS	Contact for details

Quality Control

Our 3-Propanoyl-5-Bromo-Benzo[B]Thiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.