Description

2-Thiophenecarbonitrile, 5-(1-Hydroxyethyl)- (9Ci) is a specialized heterocyclic building block featuring both nitrile and hydroxymethyl functional groups on a thiophene core. This unique molecular architecture makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a crucial building block for creating new generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Used in the synthesis of functional polymers, liquid crystals, and organic semiconductors due to the electron-rich thiophene moiety.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Fine Chemical Production: Acts as a precursor for other high-value specialty chemicals and advanced intermediates in custom synthesis projects.

Basic Information

Product Name	2-Thiophenecarbonitrile, 5-(1-Hydroxyethyl)- (9Ci)
CAS No.	353282-69-6
Molecular Formula	C7H7NOS
Molecular Weight	153.20 g/mol
Synonyms	5-(1-Hydroxyethyl)thiophene-2-carbonitrile; 5-(1-Hydroxyethyl)-2-thiophenecarbonitrile; 2-Cyano-5-(1-hydroxyethyl)thiophene; 5-(1-Hydroxyethyl)-2-cyanothiophene; α-Methyl-2-cyanothiophene-5-methanol; (5-Cyano-2-thienyl)methylcarbinol; 353282-69-6 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarbonitrile, 5-(1-Hydroxyethyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.