Description

2,3,4,6-Tetra-o-Acetyl-α-D-Galactopyranosyl Trichloroacetimidate is a high-purity glycosyl donor, a critical building block in synthetic carbohydrate chemistry. Its primary value lies in enabling the stereoselective construction of complex oligosaccharides and glycoconjugates, which are essential for pharmaceutical and biochemical research. This compound is particularly vital for researchers and manufacturers in the pharmaceutical industry developing novel therapeutics, diagnostic agents, and vaccine components, as well as for academic institutions engaged in glycoscience.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex carbohydrate-based drugs, including antiviral and anticancer agents.
• Glycoconjugate Synthesis: Used in the preparation of glycoproteins, glycolipids, and neoglycoconjugates for immunological studies and vaccine development.
• Oligosaccharide Assembly: Enables the precise, stereocontrolled formation of α-galactosidic linkages in automated and manual solid-phase oligosaccharide synthesis.
• Biochemical Probe Development: Serves as a precursor for labeled galactose derivatives used in metabolic pathway tracing and enzyme activity assays.
• Glycochip and Microarray Fabrication: Provides activated galactose units for immobilization onto surfaces to study carbohydrate-protein interactions.
• Standards and Reference Materials: Used as a high-purity standard in analytical laboratories for method development and quality control of carbohydrate APIs.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-α-D-Galactopyranosyl Trichloroacetimidate
CAS No.	353264-42-3
Molecular Formula	C16H20Cl3NO9
Molecular Weight	492.69 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl trichloroacetimidate; α-D-Galactopyranose, 2,3,4,6-tetraacetate, 1-[2,2,2-trichloroethanimidate]; Galactosyl Trichloroacetimidate, Peracetylated; 1-O-Trichloroacetimidoyl-2,3,4,6-tetra-O-acetyl-α-D-galactopyranose; Peracetylated α-D-Galactosyl Trichloroacetimidate; TCA Galactose Donor; Ac4Galα-TCA; α-Gal-TCA
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-α-D-Galactopyranosyl Trichloroacetimidate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and optical rotation measurement to ensure stereochemical integrity and batch-to-batch consistency. Certificates of Analysis (COA) with full analytical data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, containers should be sealed under an inert atmosphere (e.g., nitrogen or argon) after opening and allowed to equilibrate to room temperature before use to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	+105° to +115° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.