Description

(S)-4,5,5-Triphenyloxazolidin-2-One CAS NO 352534-92-0 is a high-value, enantiomerically pure chiral auxiliary and building block used in asymmetric synthesis. Its significance lies in its ability to induce stereoselectivity in critical bond-forming reactions, enabling the production of single-enantiomer compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity chiral intermediates.

Application

• Asymmetric Synthesis: Employed as a chiral auxiliary in aldol, alkylation, and Diels-Alder reactions to control stereochemistry.
• Pharmaceutical Intermediates: Key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemical configurations.
• Agrochemical Development: Used in the research and production of enantiomerically pure herbicides, fungicides, and insecticides.
• Catalyst and Ligand Preparation: Serves as a precursor for novel chiral catalysts and ligands used in homogeneous catalysis.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry and process chemistry laboratories.
• Fine Chemical Production: Integral to the manufacture of complex, high-value specialty chemicals where optical purity is paramount.

Basic Information

Product Name	(S)-4,5,5-Triphenyloxazolidin-2-One
CAS No.	352534-92-0
Molecular Formula	C21H17NO2
Molecular Weight	315.37 g/mol
Synonyms	(S)-4,5,5-Triphenyl-2-oxazolidinone; (S)-Triphenyloxazolidinone; (S)-2-Oxo-4,5,5-triphenyl-3-oxazolidine; (S)-N-Phenyl-C,C-diphenyloxazolidinone; Evans Chiral Auxiliary (S-isomer); (4S)-4,5,5-Triphenyl-1,3-oxazolidin-2-one; (S)-4,5,5-Triphenyloxazolidinone
EINECS	Contact for details

Quality Control

Our (S)-4,5,5-Triphenyloxazolidin-2-One is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity, and identity confirmation. We adhere to cGMP principles where applicable, and our quality commitment ensures the material meets the stringent requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.