Description

5-Formyl-4-Methylthiophene-2-Boronic Acid, 97% is a high-purity, multifunctional heterocyclic building block essential for modern synthetic chemistry. This compound is valued for its dual reactive sites—the formyl group and the boronic acid moiety—enabling its use in pivotal carbon-carbon bond-forming reactions. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and complex bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its thiophene core for enhanced biological activity.
• Material Science Research: Serves as a building block for creating conjugated polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Chemical Biology & Proteomics: Employed in the development of molecular probes, inhibitors, and bioconjugation reagents due to its reactive aldehyde functionality.
• Ligand & Catalyst Development: Utilized in the design and synthesis of novel ligands for transition metal catalysis and organocatalysis.
• Custom Synthesis & Contract Manufacturing: An important starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	5-Formyl-4-Methylthiophene-2-Boronic Acid, 97%
CAS No.	352530-25-7
Molecular Formula	C7H9BO3S
Molecular Weight	183.02 g/mol
Synonyms	(5-Formyl-4-methylthiophen-2-yl)boronic acid; 4-Methyl-5-formylthiophene-2-boronic acid; 2-Borono-4-methyl-5-formylthiophene; 5-Formyl-4-methyl-2-thienylboronic acid; 352530-25-7; 4-Methyl-5-formyl-2-thiopheneboronic acid
EINECS	Contact for details

Quality Control

Our 5-Formyl-4-Methylthiophene-2-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure a consistent purity of 97% (min.) and compliance with stringent impurity profiles. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent levels is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	97% min.
Water Content (KF)	< 1.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.