Description

S(+)-2-Amino-1-Propanol-3,3,3-D3 is a chiral, deuterium-labeled derivative of 2-amino-1-propanol, a valuable building block in synthetic organic chemistry. This compound is specifically designed for applications requiring isotopic labeling, such as internal standards for mass spectrometry and mechanistic studies in drug metabolism and pharmacokinetics (DMPK). It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry industries who require high-purity, isotopically labeled intermediates to trace molecular pathways and ensure analytical accuracy.

Application

• Pharmaceutical Research & Development: As a deuterium-labeled intermediate in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for metabolic stability studies and tracer experiments.
• Analytical Chemistry: Used as a high-purity internal standard for the accurate quantification of related compounds via Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS).
• Metabolomics & Biomarker Discovery: A critical tool for tracking and identifying metabolites in complex biological systems, aiding in disease research and diagnostic development.
• Agrochemical Development: Employed in the synthesis of labeled agrochemicals to study environmental fate, degradation pathways, and residue analysis.
• Mechanistic Organic Chemistry: Serves as a probe in kinetic isotope effect (KIE) studies to elucidate reaction mechanisms and transition states.
• Process Chemistry: Utilized in the development and optimization of synthetic routes for chiral amines under Good Manufacturing Practice (GMP) conditions where labeled compounds are required.

Basic Information

Product Name	S(+)-2-Amino-1-Propanol-3,3,3-D3
CAS No.	352438-84-7
Molecular Formula	C₃H₆D₃NO
Molecular Weight	92.14 g/mol
Synonyms	(S)-(+)-1-Amino-2-propanol-3,3,3-d3; (S)-2-Aminopropan-1-ol-3,3,3-d3; (2S)-1-Aminopropan-2-ol-3,3,3-d3; L-Alaninol-3,3,3-d3; (S)-1-Amino-2-hydroxypropane-3,3,3-d3; Deuterated (S)-2-Amino-1-propanol; (S)-2-Amino-1-propanol-d3
EINECS	Contact for details

Quality Control

Every batch of S(+)-2-Amino-1-Propanol-3,3,3-D3 is produced and analyzed under strict quality protocols to ensure exceptional isotopic and chemical purity for sensitive research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for chiral purity, isotopic enrichment, and chemical assay.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation upon prolonged exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Isotopic Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.