Description

1,3-Propanediamine-2,2-D2 is a deuterated analog of 1,3-diaminopropane, where two hydrogen atoms at the 2-position are replaced with deuterium, a stable isotope of hydrogen. This isotopic labeling makes it an essential tool in advanced research, particularly in mechanistic studies and analytical method development using techniques like NMR spectroscopy and mass spectrometry. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications requiring precise molecular tracking and stable isotope labeling.

Application

• Pharmaceutical Research & Development: As a deuterated building block for the synthesis of isotopically labeled active pharmaceutical ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Analytical Chemistry Standards: Serving as an internal standard or reference material in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) analysis to ensure accuracy and reproducibility.
• Mechanistic Studies: Employed in reaction mechanism elucidation, where deuterium acts as a tracer to follow reaction pathways and identify intermediates.
• Agrochemical Development: Used in the synthesis of labeled agrochemicals to study environmental fate, degradation pathways, and residue analysis.
• Material Science: As a precursor or modifier in the development of specialized polymers and advanced materials where isotopic purity can influence physical properties.
• Metabolomics & Proteomics: Facilitating stable isotope labeling by amino acids in cell culture (SILAC) and other techniques for quantitative analysis of biological systems.

Basic Information

Product Name	1,3-Propanediamine-2,2-D2
CAS No.	352438-78-9
Molecular Formula	C3H8D2N2
Molecular Weight	78.14 g/mol
Synonyms	1,3-Diaminopropane-2,2-d2; 1,3-Propanediamine-d2 (2,2); 2,2-Dideutero-1,3-propanediamine; 1,3-Diaminopropane-d2; [2,2-2H2]-1,3-Propanediamine; Propane-1,3-diamine-2,2-d2; Deuterated Trimethylenediamine; D2-1,3-Diaminopropane
EINECS	Contact for details

Quality Control

Every batch of 1,3-Propanediamine-2,2-D2 is produced and analyzed under strict quality protocols to ensure high isotopic and chemical purity suitable for research applications. Our quality assurance includes comprehensive testing for identity, assay, isotopic enrichment, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or Titration)	≥ 98.0%
Isotopic Enrichment (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Related Substances (GC or HPLC)	≤ 1.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.