Description

Heptadecanoic-D33 Acid is a fully deuterated isotopologue of margaric acid, where all 33 hydrogen atoms are replaced with deuterium. This high isotopic purity makes it an essential internal standard and tracer in quantitative mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. It is critical for researchers and analytical laboratories in pharmaceutical development, lipidomics, and metabolic studies requiring precise quantification and pathway elucidation.

Application

• Internal Standard for Mass Spectrometry (MS): Provides unmatched accuracy for the quantification of long-chain fatty acids and their derivatives in complex biological matrices like plasma, tissues, and cell cultures.
• Metabolic Tracer Studies: Used in stable isotope labeling experiments to track fatty acid metabolism, absorption, and β-oxidation pathways in vivo and in vitro.
• NMR Spectroscopy: Serves as a valuable reference compound in deuterium NMR for structural analysis and dynamics studies of lipid assemblies and membranes.
• Pharmaceutical Research: Supports drug discovery and development, particularly for metabolic diseases, by enabling precise measurement of lipid biomarkers and drug metabolites.
• Lipidomics and Biomarker Discovery: Essential for high-throughput profiling of lipids to identify disease-specific signatures in clinical and preclinical research.
• Quality Control & Method Validation: Employed in analytical method development and validation to ensure accuracy, precision, and compliance with regulatory guidelines (e.g., FDA, EMA).

Basic Information

Product Name	Heptadecanoic-D33 Acid
CAS No.	352431-41-5
Molecular Formula	C17D33O2 or C17H0D33CO2H
Molecular Weight	Approx. 291.55 g/mol
Synonyms	Margaric Acid-d33; Heptadecanoic-d33 Acid; n-Heptadecanoic-d33 Acid; Deuterated Margaric Acid; C17:0-d33 Fatty Acid; Heptadecanoic Acid (33-d); Perdeuterated Heptadecanoic Acid; Isotopic Standard C17-d33
EINECS	Contact for details

Quality Control

Every batch of Heptadecanoic-D33 Acid is manufactured and analyzed under strict quality systems to ensure exceptional isotopic and chemical purity for critical research applications. Our products undergo rigorous quality testing, including NMR, MS, and HPLC analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), chemical purity, and analytical methods are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Isotopic Purity (Atom % D)	≥ 98%
Chemical Purity (HPLC)	≥ 98%
Melting Point	Contact for details
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.