Description

Glyceryl Tri(Octanoate-2,2-D2) is a deuterated analog of glyceryl trioctanoate (tricaprylin), where specific hydrogen atoms on the fatty acid chains have been replaced with deuterium. This isotopic labeling is critical for advanced research and analytical applications where precise molecular tracking and differentiation are required. It is an essential material for scientists in pharmaceutical development, metabolic studies, and analytical chemistry who require high-purity, isotopically labeled standards and reagents.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a stable isotope-labeled internal standard for the accurate quantification of medium-chain triglycerides (MCTs) and their metabolites in complex biological matrices via LC-MS/MS.
• Metabolic Pathway Tracing: Employed in pharmacokinetic and lipid metabolism studies to trace the absorption, distribution, and metabolism of dietary fats using deuterium as a non-radioactive tracer.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the quality control and validation of analytical methods in drug formulation, particularly for lipid-based drug delivery systems.
• NMR Spectroscopy Studies: Utilized as a probe in Nuclear Magnetic Resonance (NMR) spectroscopy to investigate molecular structure, dynamics, and interactions without signal interference from protonated species.
• Nutritional Science Research: Applied in clinical and preclinical research to study the precise metabolic fate of medium-chain fatty acids and their impact on energy metabolism.
• Chemical Synthesis Intermediate: Acts as a specialized building block for the synthesis of more complex, deuterated lipids and bioactive molecules for research purposes.

Basic Information

Product Name	Glyceryl Tri(Octanoate-2,2-D2)
CAS No.	352431-34-6
Molecular Formula	C27H47D6O6
Molecular Weight	~485.7 g/mol
Synonyms	Tricaprylin-2,2-D2; 1,2,3-Tri[(2,2-D2)octanoyloxy]propane; Glycerol Trioctanoate-d6; Deuterated Tricaprylin; Octanoic-2,2-d2 Acid, 1,2,3-Propanetriyl Ester; MCT-d6; Glyceryl Tricaprylate-d6
EINECS	Contact for details

Quality Control

Every batch of Glyceryl Tri(Octanoate-2,2-D2) is manufactured and analyzed under strict quality management systems to ensure the highest isotopic and chemical purity for research applications. Our quality commitment includes comprehensive characterization by NMR, MS, and HPLC to verify deuterium incorporation, chemical identity, and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific data.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Colorless to pale yellow oily liquid
Identification (NMR)	Conforms to structure
Isotopic Purity (Deuterium Incorporation)	≥ 98 atom % D (by NMR/MS)
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.