Description

2-Imidazolidinethione-4,5-D4 is a deuterated derivative of 2-imidazolidinethione, a key heterocyclic compound. This isotopically labeled version is essential for advanced research and development, particularly in analytical chemistry and pharmaceutical studies. It is primarily used by scientists and manufacturers in the fields of deuterated NMR spectroscopy, mass spectrometry, and as a stable-isotope labeled intermediate for metabolic and pharmacokinetic research.

Application

• Deuterated NMR Solvent & Reagent: Used as an internal standard or shift reagent in nuclear magnetic resonance (NMR) spectroscopy for precise structural analysis.
• Mass Spectrometry Standards: Serves as a stable-isotope labeled internal standard in LC-MS and GC-MS for accurate quantitative analysis.
• Pharmaceutical Research: A critical building block in the synthesis of deuterated drug candidates for improved metabolic stability and pharmacokinetic studies (DMPK).
• Chemical Synthesis Intermediate: Employed in organic synthesis to introduce deuterium labels into more complex molecules for tracing and mechanistic studies.
• Metabolic Pathway Tracing: Utilized in biochemical research to track and elucidate metabolic pathways in biological systems.
• Material Science Research: Potential use in the development of specialized polymers or materials where deuterium incorporation modifies physical properties.

Basic Information

Product Name	2-Imidazolidinethione-4,5-D4
CAS No.	352431-28-8
Molecular Formula	C3D4H2N2S
Molecular Weight	106.16 g/mol
Synonyms	Ethylene Thiourea-d4; 2-Mercaptoimidazoline-d4; 2-Thioimidazolidinone-d4; 4,5-Dideutero-2-imidazolidinethione; 1,3-Diazolidine-2-thione-4,5-d4; Imidazolidine-2-thione-4,5-d4; 2-Imidazolidinethione-d4; Deuterated Ethylene Thiourea
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced and handled under strict quality protocols to ensure isotopic purity and chemical integrity. Each batch is analyzed using advanced techniques including NMR and Mass Spectrometry to confirm deuterium enrichment and chemical purity. Certificates of Analysis (COA) detailing isotopic purity (D-enrichment), chemical purity (HPLC/GC), and other relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.