Description

n-Butane-1,1,2,2,3,3,4,4-D8 is a fully deuterated isotopologue of n-butane, where all eight hydrogen atoms are replaced by deuterium (²H). This high-purity, stable isotope-labeled compound is essential for advanced analytical and research applications where precise molecular tracking and minimal background interference are required. It is primarily utilized by researchers and scientists in the fields of analytical chemistry, spectroscopy, and materials science for use as an internal standard, tracer, or solvent in NMR and mass spectrometry studies.

Application

• NMR Spectroscopy Solvent & Internal Standard: Serves as a critical, chemically inert solvent and reference standard for high-resolution nuclear magnetic resonance (NMR) analysis, providing a deuterium lock signal and enabling precise chemical shift measurements.
• Mass Spectrometry Tracer Studies: Used as a stable, non-radioactive isotopic tracer in mass spectrometry (MS) and gas chromatography-mass spectrometry (GC-MS) for metabolic pathway analysis, reaction mechanism studies, and quantitative analysis.
• Chemical Reaction & Kinetic Studies: Employed in mechanistic studies to investigate reaction pathways, isotope effects, and kinetics in organic and organometallic chemistry due to its distinct isotopic signature.
• Polymer & Materials Science Research: Acts as a probe or precursor in the study of polymer dynamics, diffusion processes, and the structure-property relationships of advanced materials.
• Pharmaceutical Research & Development: Utilized in drug metabolism and pharmacokinetics (DMPK) studies to trace the fate of drug molecules and their metabolites within biological systems.
• Analytical Method Development & Validation: Provides a high-purity standard for developing, calibrating, and validating sensitive analytical methods in regulatory and quality control environments.

Basic Information

Product Name	n-Butane-1,1,2,2,3,3,4,4-D8
CAS No.	352431-08-4
Molecular Formula	C4D8
Molecular Weight	64.17 g/mol
Synonyms	Perdeuterated n-Butane; n-Butane-d8; [²H8]Butane; Butane-D8; Deuterated Butane; Fully Deuterated Butane; 1,1,2,2,3,3,4,4-Octadeuteriobutane; C4D8
EINECS	Contact for details

Quality Control

Our n-Butane-1,1,2,2,3,3,4,4-D8 is manufactured and handled under stringent conditions to ensure the highest isotopic and chemical purity. Each batch is subjected to rigorous analytical testing, including NMR and GC-MS, to verify identity, isotopic enrichment (typically >98 atom % D), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and gaseous nature at room temperature, this material is supplied in a sealed, pressurized cylinder or ampule. Store in a cool, well-ventilated area away from heat, sparks, and open flames. The container should be kept upright and secured to prevent damage. Use appropriate safety measures when handling compressed gases.

Specification

Item	Specification
Appearance	Colorless Gas
Identification (NMR)	Conforms to Structure
Isotopic Purity (Atom % D)	≥ 98%
Chemical Purity (GC)	≥ 99%
Assay (NMR/GC-MS)	≥ 99%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.