Description

2-Amino-6-Ethyl-4,5,6,7-Tetrahydro-Benzo[B]-Thiophene-3-Carboxylic Acid Methyl Ester is a high-value, heterocyclic organic building block with a fused tetrahydrobenzothiophene core. This compound is a critical intermediate in the synthesis of complex molecules, prized for its structural versatility and functional groups that enable further chemical modifications. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in advanced display technologies.
• Material Science Research: Employed in the development of organic semiconductors and other functional materials due to its conjugated system potential.
• Academic & Industrial R&D: A versatile scaffold for medicinal chemistry and synthetic organic chemistry research programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2-Amino-6-Ethyl-4,5,6,7-Tetrahydro-Benzo[B]-Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	351980-88-6
Molecular Formula	C₁₄H₁₉NO₂S
Molecular Weight	265.37 g/mol
Synonyms	Methyl 2-amino-6-ethyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 6-Ethyl-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid methyl ester; 2-Amino-6-ethyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid methyl ester; Ethyl-tetrahydro-benzothiophene methyl ester; ATBCME; CAS 351980-88-6
EINECS	Contact for details

Quality Control

Our production of 2-Amino-6-Ethyl-4,5,6,7-Tetrahydro-Benzo[B]-Thiophene-3-Carboxylic Acid Methyl Ester adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the exacting standards required for pharmaceutical and advanced chemical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.