Description

2-Amino-6-tert-Butyl-4,5,6,7-Tetrahydro-Benzo[ B ]Thiophene-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those with central nervous system (CNS) or anti-inflammatory targets.
• Agrochemical Research: Used as a building block for developing new active ingredients in crop protection and pesticide formulations.
• Organic Synthesis Scaffold: Provides a versatile fused-ring thiophene core for medicinal chemistry and combinatorial library development.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.
• Academic & Contract Research: Utilized in university and CRO laboratories for fundamental research in heterocyclic chemistry and reaction mechanism studies.

Basic Information

Product Name	2-Amino-6-tert-Butyl-4,5,6,7-Tetrahydro-Benzo[ B ]Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	351980-73-9
Molecular Formula	C15H23NO2S
Molecular Weight	281.41 g/mol
Synonyms	Ethyl 2-Amino-6-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-Amino-6-tert-butyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester; 6-tert-Butyl-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester; CAS 351980-73-9; Ethyl 2-amino-6-(tert-butyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 6-(1,1-Dimethylethyl)-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Amino-6-tert-Butyl-4,5,6,7-Tetrahydro-Benzo[ B ]Thiophene-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.