Description

1,10-Phenanthroline Maleimide is a high-purity, bifunctional organic compound that combines the metal-chelating properties of a phenanthroline moiety with the thiol-reactive capability of a maleimide group. This unique structure makes it an invaluable cross-linking and conjugation reagent for advanced material science and bioconjugation applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors for developing novel sensors, catalysts, and functionalized biomolecules.

Application

• Bioconjugation and Protein Labeling: Site-specific modification of cysteine residues in antibodies, enzymes, and other proteins for drug delivery systems and diagnostic assays.
• Polymer and Material Science: Synthesis of functional polymers, hydrogels, and smart materials via thiol-ene "click" chemistry reactions.
• Catalyst and Ligand Design: Creation of novel transition metal complexes for catalytic applications and as building blocks for supramolecular chemistry.
• Fluorescent Probe Development: Construction of turn-on or ratiometric fluorescent sensors for metal ion detection based on the phenanthroline fluorophore.
• Surface Functionalization: Immobilization of biomolecules or catalysts onto gold or other thiol-presenting surfaces for biosensor and chip fabrication.
• Cross-linking Agent: For stabilizing protein structures or creating protein-protein conjugates in structural biology studies.

Basic Information

Product Name	1,10-Phenanthroline Maleimide
CAS No.	351870-31-0
Molecular Formula	C20H12N2O2
Molecular Weight	312.33 g/mol
Synonyms	1,10-Phenanthrolin-5-yl Maleimide; 5-Maleimido-1,10-phenanthroline; N-(1,10-Phenanthrolin-5-yl)maleimide; 1,10-Phenanthroline-5-maleimide; Maleimide-Phenanthroline Conjugate; Phen-Mal; Phenanthroline Maleimide Crosslinker
EINECS	Contact for details

Quality Control

Our 1,10-Phenanthroline Maleimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light may lead to decomposition or reduced reactivity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.