Description

5-Aminopentyl Methanthiosulfonate Hydrobromide is a specialized organic salt compound with the CAS number 351422-76-9. This chemical is a valuable intermediate and building block in advanced organic synthesis, particularly for introducing protected thiol functionalities. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, biochemical probes, and materials science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting cysteine residues or requiring thiol-based conjugation.
• Bioconjugation Reagent: Used for the site-specific modification of proteins, peptides, and antibodies, enabling the creation of antibody-drug conjugates (ADCs) and diagnostic probes.
• Chemical Biology Research: Serves as a critical tool for studying protein function, enzyme inhibition, and cellular pathways through controlled thiol-disulfide exchange reactions.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent in the development of smart polymers, hydrogels, and surface coatings with responsive properties.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis to incorporate methanethiosulfonate-protected cysteine analogs, facilitating specific disulfide bond formation.

Basic Information

Product Name	5-Aminopentyl Methanthiosulfonate Hydrobromide
CAS No.	351422-76-9
Molecular Formula	C6H14NO2S2•HBr
Molecular Weight	288.22 g/mol
Synonyms	5-Aminoamyl Methanethiosulfonate Hydrobromide; 5-Aminopentyl Methanesulfonothioate HBr; (5-Aminopentyl) Methanethiosulfonate Hydrobromide; Methanethiosulfonic Acid S-(5-Aminopentyl) Ester Hydrobromide; MTSSL Precursor; Aminopentyl MTS; S-(5-Aminopentyl) Methanethiosulfonate Hydrobromide
EINECS	Contact for details

Quality Control

Our 5-Aminopentyl Methanthiosulfonate Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications in GMP-compliant pharmaceutical development and high-precision research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.