Description

2-[2-(1,2-Dimethyl-1H-Indol-3-Yl)Vinyl]-3-(4-Methylphenyl)-4(3H)-Quinazolinone is a high-purity, advanced pharmaceutical intermediate and research chemical of significant interest in medicinal chemistry. This compound is valued for its complex heterocyclic structure, which serves as a key building block in the synthesis of novel bioactive molecules. It is primarily utilized by R&D laboratories and pharmaceutical manufacturers focused on developing new therapeutic agents, particularly in oncology and neurological research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses due to its reactive vinyl and quinazolinone functionalities.
• Biochemical Probe Development: Serves as a starting material for creating labeled compounds or probes for biological assay development.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory chemical and pharmacological studies.
• Contract Research Organization (CRO) Projects: Supplied to CROs engaged in custom synthesis and early-stage drug discovery for clients.

Basic Information

Product Name	2-[2-(1,2-Dimethyl-1H-Indol-3-Yl)Vinyl]-3-(4-Methylphenyl)-4(3H)-Quinazolinone
CAS No.	351338-18-6
Molecular Formula	C27H23N3O
Molecular Weight	405.49 g/mol
Synonyms	3-(4-Methylphenyl)-2-[2-(1,2-dimethyl-1H-indol-3-yl)ethenyl]-4(3H)-quinazolinone; 2-[2-(1,2-Dimethylindol-3-yl)vinyl]-3-(p-tolyl)quinazolin-4(3H)-one; 4(3H)-Quinazolinone, 2-[2-(1,2-dimethyl-1H-indol-3-yl)ethenyl]-3-(4-methylphenyl)-; CAS 351338-18-6
EINECS	Contact for details

Quality Control

Every batch of 2-[2-(1,2-Dimethyl-1H-Indol-3-Yl)Vinyl]-3-(4-Methylphenyl)-4(3H)-Quinazolinone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) with specifications for assay, related substances, and residual solvents is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.