Description

2-Acetyl-6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex alkaloids and potential drug candidates targeting the central nervous system.
• Organic Synthesis Building Block: Used in research and development for constructing complex molecular architectures, particularly in medicinal chemistry.
• Agrochemical Research: Serves as a starting material for developing novel crop protection agents and herbicides.
• Biochemical Research: Employed in studies involving enzyme inhibitors or receptor ligands due to its specific isoquinoline scaffold.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals requiring high-purity, complex intermediates.

Basic Information

Product Name	2-Acetyl-6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Ethyl Ester
CAS No.	351198-20-4
Molecular Formula	C₁₆H₂₁NO₅
Molecular Weight	307.34 g/mol
Synonyms	Ethyl 2-Acetyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylate; 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-[(ethoxycarbonyl)methyl]-2-isoquinolinecarboxylic Acid; 2-Acetyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic Acid Ethyl Ester; 1-Carbethoxy-2-acetyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; CAS 351198-20-4
EINECS	Contact for details

Quality Control

Our 2-Acetyl-6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.