Description

3-Chloro-6-Ethyl-1-Benzothiophene-2-Carboxylic Acid is a high-purity, synthetically valuable heterocyclic building block used in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and functional materials due to its unique benzothiophene core with strategically positioned chloro and carboxylic acid substituents. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and advanced light-emitting materials.
• Ligand and Catalyst Development: The carboxylic acid functionality allows for derivatization into chelating ligands for metal-organic frameworks (MOFs) or catalytic complexes.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Chloro-6-Ethyl-1-Benzothiophene-2-Carboxylic Acid
CAS No.	351000-45-8
Molecular Formula	C11H9ClO2S
Molecular Weight	240.70 g/mol
Synonyms	3-Chloro-6-ethylbenzo[b]thiophene-2-carboxylic acid; 2-Benzothiophenecarboxylic acid, 3-chloro-6-ethyl-; 351000-45-8; 3-Chloro-6-ethyl-1-benzothiophene-2-carboxylic acid; 3-Chloro-6-ethylbenzothiophene-2-carboxylic acid; 6-Ethyl-3-chlorobenzothiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Ethyl-1-Benzothiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.