Description

Ethyl 2-Amino-5-Methyl-4-(4-Methylphenyl)Thiophene-3-Carboxylate is a high-purity, functionalized thiophene derivative serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a versatile scaffold for constructing complex heterocyclic systems, enabling the development of novel compounds with targeted properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, leveraging the thiophene core for bioactivity.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Dye and Pigment Synthesis: Acts as an intermediate for creating specialized heterocyclic dyes and organic pigments with specific color and stability properties.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical reactions in heterocyclic and organosulfur chemistry.

Basic Information

Product Name	Ethyl 2-Amino-5-Methyl-4-(4-Methylphenyl)Thiophene-3-Carboxylate
CAS No.	350997-35-2
Molecular Formula	C15H17NO2S
Molecular Weight	275.36 g/mol
Synonyms	Ethyl 2-Amino-5-Methyl-4-(p-Tolyl)Thiophene-3-Carboxylate; 2-Amino-5-methyl-4-(4-methylphenyl)thiophene-3-carboxylic acid ethyl ester; 4-(4-Methylphenyl)-5-methyl-2-aminothiophene-3-carboxylic acid ethyl ester; 3-Thiophenecarboxylic acid, 2-amino-5-methyl-4-(4-methylphenyl)-, ethyl ester; Ethyl α-Amino-5-methyl-4-(p-tolyl)thiophene-3-carboxylate; p-Tolyl Thiophene Ester Intermediate
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-Amino-5-Methyl-4-(4-Methylphenyl)Thiophene-3-Carboxylate adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and tested against rigorous internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.