Description

2-Amino-5-Methyl-4-p-Tolyl-Thiophene-3-Carboxylic Acid Methyl Ester is a high-value, multi-functional thiophene derivative serving as a critical building block in advanced organic synthesis. Its molecular architecture makes it an essential intermediate for the development of novel pharmaceuticals and specialty chemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its thiophene core for bioactive molecule design.
• Material Science Research: Serves as a monomer or building block for developing organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized thiophene-based dyes and colorants.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies in heterocyclic chemistry and scaffold diversification.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	2-Amino-5-Methyl-4-p-Tolyl-Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	350997-34-1
Molecular Formula	C15H17NO2S
Molecular Weight	275.36 g/mol
Synonyms	Methyl 2-amino-5-methyl-4-(4-methylphenyl)thiophene-3-carboxylate; 2-Amino-5-methyl-4-(p-tolyl)thiophene-3-carboxylic acid methyl ester; 4-(4-Methylphenyl)-2-amino-5-methylthiophene-3-carboxylic acid methyl ester; 350997-34-1; Thiophene-3-carboxylic acid, 2-amino-5-methyl-4-(4-methylphenyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Methyl-4-p-Tolyl-Thiophene-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.