Description

Isopropyl 2-Amino-4-(4-Fluorophenyl)Thiophene-3-Carboxylate is a high-purity, synthetically valuable heterocyclic building block. This compound is a critical intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and fluorophenyl motifs.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and liquid crystals due to its conjugated thiophene core.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks and exploring new chemical reactions.
• Bioconjugation & Probe Development: The amino and ester functional groups allow for further derivatization to create fluorescent probes or biochemical tools.

Basic Information

Product Name	Isopropyl 2-Amino-4-(4-Fluorophenyl)Thiophene-3-Carboxylate
CAS No.	350997-28-3
Molecular Formula	C14H14FNO2S
Molecular Weight	279.33 g/mol
Synonyms	2-Amino-4-(4-fluorophenyl)thiophene-3-carboxylic acid isopropyl ester; Isopropyl 2-amino-4-(p-fluorophenyl)thiophene-3-carboxylate; 4-(4-Fluorophenyl)-2-aminothiophene-3-carboxylic Acid Isopropyl Ester; 350997-28-3; 2-Amino-4-(4-fluorophenyl)-3-thiophenecarboxylic acid 1-methylethyl ester; Isopropyl α-amino-4-fluorophenylthiophene-3-carboxylate; p-Fluorophenyl substituted aminothiophene carboxylate
EINECS	Contact for details

Quality Control

Our Isopropyl 2-Amino-4-(4-Fluorophenyl)Thiophene-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.