Description

2-Amino-4-Biphenyl-4-Yl-Thiophene-3-Carboxylic Acid Methyl Ester is a high-value heterocyclic organic compound featuring a thiophene core substituted with amino, biphenyl, and ester functional groups. This unique molecular architecture makes it a critical advanced intermediate in the synthesis of complex pharmaceuticals and functional materials. It is primarily sought by research institutions and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs) and organic electronic components.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders and oncology.
• Organic Semiconductor Research: Used in the development of organic field-effect transistors (OFETs) and photovoltaic materials due to its conjugated thiophene-biphenyl system.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorescent Dye & Sensor Development: Employed in the research and production of fluorescent probes and chemosensors for biological and environmental detection.
• Agrochemical Intermediate: Utilized in the research phase for developing new generation herbicides and fungicides with specific modes of action.
• Material Science: Investigated for use in nonlinear optical (NLO) materials and as a component in advanced polymer composites.

Basic Information

Item	Detail
Product Name	2-Amino-4-Biphenyl-4-Yl-Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	350997-16-9
Molecular Formula	C24H19NO2S
Molecular Weight	385.48 g/mol
Synonyms	Methyl 2-Amino-4-(4-biphenylyl)thiophene-3-carboxylate; 2-Amino-4-(biphenyl-4-yl)thiophene-3-carboxylic acid methyl ester; 4-Biphenyl-4-yl-2-amino-thiophene-3-carboxylic acid methyl ester; 350997-16-9; AKOS BRN-0715; BRN 0715; Methyl 2-amino-4-[1,1'-biphenyl]-4-yl-3-thiophenecarboxylate; 3-Thiophenecarboxylic acid, 2-amino-4-(1,1'-biphenyl-4-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of 2-Amino-4-Biphenyl-4-Yl-Thiophene-3-Carboxylic Acid Methyl Ester adheres to stringent cGMP guidelines where applicable, ensuring batch-to-batch consistency and traceability. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via NMR and MS. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to minimize contact with moisture and atmospheric oxygen.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.