Description

2-Amino-4-(4-Cyclohexyl-Phenyl)-Thiophene-3-Carboxylic Acid Methyl Ester is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a thiophene core with amino and ester functionalities, enabling its use in the development of complex, high-value molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or functional additive in the research of conductive polymers and organic semiconductors (OLEDs, OFETs).
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization, including Suzuki coupling, amidation, and hydrolysis reactions to create diverse chemical libraries.
• Dye & Pigment Industry: Employed in the research of organic dyes and pigments due to the electron-rich thiophene system.

Basic Information

Product Name	2-Amino-4-(4-Cyclohexyl-Phenyl)-Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	350997-15-8
Molecular Formula	C18H21NO2S
Molecular Weight	315.43 g/mol
Synonyms	Methyl 2-amino-4-(4-cyclohexylphenyl)thiophene-3-carboxylate; 2-Amino-4-(4-cyclohexylphenyl)-3-thiophenecarboxylic acid methyl ester; 4-(4-Cyclohexylphenyl)-2-aminothiophene-3-carboxylic acid methyl ester; Thiophene-3-carboxylic acid, 2-amino-4-(4-cyclohexylphenyl)-, methyl ester; 350997-15-8; Methyl 2-amino-4-(4-cyclohexylphenyl)-3-thiophenecarboxylate
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Cyclohexyl-Phenyl)-Thiophene-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.