Description

Methyl 2-Amino-4-(4-Fluorophenyl)Thiophene-3-Carboxylate is a high-value, multi-functional heterocyclic building block featuring a thiophene core substituted with an amino group, a fluorophenyl ring, and a methyl ester. This compound matters for its critical role as a versatile intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and fluorophenyl motifs.
• Material Science: Used in the research and development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene structure.
• Chemical Synthesis: Employed in organic synthesis for further functionalization, such as hydrolysis to the corresponding acid, amide coupling, or cyclization reactions to create more complex fused heterocycles.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and Contract Research Organizations (CROs) exploring new chemical entities and structure-activity relationships (SAR).

Basic Information

Product Name	Methyl 2-Amino-4-(4-Fluorophenyl)Thiophene-3-Carboxylate
CAS No.	350997-12-5
Molecular Formula	C12H10FNO2S
Molecular Weight	251.28 g/mol
Synonyms	Methyl 2-Amino-4-(4-fluorophenyl)thiophene-3-carboxylate; 2-Amino-4-(4-fluorophenyl)thiophene-3-carboxylic acid methyl ester; Methyl 2-amino-4-(p-fluorophenyl)thiophene-3-carboxylate; 3-Thiophenecarboxylic acid, 2-amino-4-(4-fluorophenyl)-, methyl ester; 350997-12-5; Methyl 2-amino-4-(4'-fluorophenyl)thiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-4-(4-Fluorophenyl)Thiophene-3-Carboxylate undergoes rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support your research and development needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for every batch, ensuring traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.