Description

2-Amino-4-p-Tolyl-Thiophene-3-Carboxylic Acid Methyl Ester is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex heterocyclic compounds, enabling research and development across multiple high-tech industries. This intermediate is essential for pharmaceutical chemists, agrochemical researchers, and material scientists developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or functional unit in the creation of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Dye & Pigment Synthesis: Acts as a core structure for synthesizing specialized heterocyclic dyes and pigments with unique chromatic properties.
• Chemical Biology Probes: Utilized in constructing molecular probes and tags for studying biological processes and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Amino-4-p-Tolyl-Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	350997-08-9
Molecular Formula	C13H13NO2S
Molecular Weight	247.31 g/mol
Synonyms	Methyl 2-amino-4-(4-methylphenyl)thiophene-3-carboxylate; 2-Amino-4-(p-tolyl)thiophene-3-carboxylic acid methyl ester; 4-(4-Methylphenyl)-2-aminothiophene-3-carboxylic acid methyl ester; 2-Amino-4-(4-methylphenyl)-3-thiophenecarboxylic acid methyl ester; 350997-08-9; Methyl 2-amino-4-p-tolylthiophene-3-carboxylate; p-Tolyl thiophene ester derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-p-Tolyl-Thiophene-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.