Description

2-Amino-4-Methyl-5-p-Tolylcarbamoyl-Thiophene-3-Carboxylic Acid Methyl Ester is a high-purity, specialized thiophene derivative serving as a critical building block in advanced organic synthesis. Its molecular architecture makes it a valuable precursor for the development of novel heterocyclic compounds with targeted biological and material properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Used in the research and development of organic semiconductors, conductive polymers, and advanced dyes.
• Chemical Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic frameworks in academic and industrial R&D.
• Ligand & Catalyst Development: Potential use in creating specialized ligands for catalytic systems or metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Amino-4-Methyl-5-p-Tolylcarbamoyl-Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	350996-97-3
Molecular Formula	C15H16N2O3S
Molecular Weight	304.36 g/mol
Synonyms	Methyl 2-amino-4-methyl-5-[(4-methylphenyl)carbamoyl]thiophene-3-carboxylate; 2-Amino-4-methyl-5-[(4-methylphenyl)carbamoyl]thiophene-3-carboxylic acid methyl ester; 5-(p-Tolylcarbamoyl)-2-amino-4-methylthiophene-3-carboxylic acid methyl ester; Thiophene-3-carboxylic acid, 2-amino-4-methyl-5-[(4-methylphenyl)carbamoyl]-, methyl ester; CAS 350996-97-3; p-Tolylcarbamoyl thiophene ester; AMTCME (abbreviation)
EINECS	Contact for details

Quality Control

Our production of 2-Amino-4-Methyl-5-p-Tolylcarbamoyl-Thiophene-3-Carboxylic Acid Methyl Ester adheres to stringent in-process controls and final batch analysis to ensure consistent high purity and chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, impurity profile, and physical characteristics. Our quality system is designed to meet the rigorous demands of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.