Description

2-Amino-5-Dimethylcarbamoyl-4-Methyl-Thiophene-3-Carboxylic Acid Methyl Ester is a high-purity, multi-functional thiophene derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals, where precise molecular architecture is paramount. It is primarily needed by research and development chemists, process scale-up engineers, and manufacturers within the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic cores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its thiophene scaffold for biological activity.
• Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, dyes, and functional materials.
• Research & Development: Essential for academic and industrial R&D focused on medicinal chemistry and new material science.
• Process Chemistry: Employed in route scouting and optimization for the scalable manufacturing of target molecules.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing client-specific compounds.

Basic Information

Product Name	2-Amino-5-Dimethylcarbamoyl-4-Methyl-Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	350996-95-1
Molecular Formula	C11H16N2O3S
Molecular Weight	256.32 g/mol
Synonyms	Methyl 2-amino-5-(dimethylcarbamoyl)-4-methylthiophene-3-carboxylate; 2-Amino-4-methyl-5-[(dimethylamino)carbonyl]thiophene-3-carboxylic acid methyl ester; 3-Thiophenecarboxylic acid, 2-amino-5-(dimethylaminocarbonyl)-4-methyl-, methyl ester; Thiophene-3-carboxylic acid derivative; CAS 350996-95-1
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Dimethylcarbamoyl-4-Methyl-Thiophene-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.