Description

2-Amino-5-Carbamoyl-4-Methyl-Thiophene-3-Carboxylic Acid Methyl Ester is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific thiophene-based motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and advanced materials due to its electron-rich thiophene core.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized dyes and functional pigments.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.
• Custom Synthesis Projects: A starting material for bespoke chemical synthesis services, enabling the production of tailored compounds for specific client needs.

Basic Information

Product Name	2-Amino-5-Carbamoyl-4-Methyl-Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	350996-94-0
Molecular Formula	C8H10N2O3S
Molecular Weight	214.24 g/mol
Synonyms	Methyl 2-Amino-5-Carbamoyl-4-Methylthiophene-3-Carboxylate; 2-Amino-4-methyl-5-carbamoylthiophene-3-carboxylic acid methyl ester; 3-Thiophenecarboxylic acid, 2-amino-5-(aminocarbonyl)-4-methyl-, methyl ester; Methyl 2-amino-4-methyl-5-carbamoyl-3-thiophenecarboxylate; 4-Methyl-2-amino-5-carbamoylthiophene-3-carboxylic acid methyl ester; Thiophene-3-carboxylic acid derivative; AMCTCME
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Carbamoyl-4-Methyl-Thiophene-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in GMP-oriented synthesis and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.