Description

2-Amino-6-Propyl-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and neurological research. It is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• API Synthesis: Serves as a critical building block in the multi-step production of active pharmaceutical ingredients for preclinical and clinical development.
• Biochemical Research: Employed in biochemical assays and as a tool compound for investigating specific biological targets and mechanisms.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for specialized, high-value chemical products.

Basic Information

Product Name	2-Amino-6-Propyl-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide
CAS No.	350996-93-9
Molecular Formula	C₁₂H₂₀N₂OS
Molecular Weight	240.36 g/mol
Synonyms	2-Amino-6-propyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide; 6-Propyl-2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; Pramipexole Intermediate; Pramipexole Impurity; Pramipexole Related Compound; SND 919 Intermediate; SND-919; U-98,528 Intermediate
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Propyl-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.