Description

2-Amino-4,5,6,7,8,9-Hexahydro-Cycloocta[B]-Thiophene-3-Carboxylic Acid Methyl Ester is a high-value, complex heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique fused ring structure, which incorporates both amino and ester functionalities, making it a versatile precursor for constructing sophisticated molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex polycyclic frameworks.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the thiophene and amino-ester motifs can impart specific biological activity.
• Material Science: Acts as a monomer or functional additive in the research of advanced polymers and organic electronic materials due to its electron-rich thiophene core.
• Chemical Biology: Employed as a scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Catalyst Ligand Synthesis: The amino and ester groups provide handles for derivatization into novel chiral or non-chiral ligands for catalytic applications.
• Academic & Institutional R&D: A key reagent for methodological studies in organic chemistry, particularly in heterocyclic and ring-expansion chemistry.

Basic Information

Product Name	2-Amino-4,5,6,7,8,9-Hexahydro-Cycloocta[B]-Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	350996-90-6
Molecular Formula	C12H17NO2S
Molecular Weight	239.33 g/mol
Synonyms	Methyl 2-amino-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxylate; 2-Amino-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxylic acid methyl ester; Cycloocta[b]thiophene-3-carboxylic acid, 2-amino-4,5,6,7,8,9-hexahydro-, methyl ester; CAS 350996-90-6; Hexahydrocyclooctathiophene methyl ester derivative; Amino-thiophene carboxylate building block
EINECS	Contact for details

Quality Control

Our 2-Amino-4,5,6,7,8,9-Hexahydro-Cycloocta[B]-Thiophene-3-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.