Description

Dl-2-Aminobutyric-D6 Acid is a deuterium-labeled isotopologue of the non-proteinogenic amino acid 2-aminobutyric acid, where six hydrogen atoms are replaced by deuterium. This compound is a critical stable isotope-labeled internal standard used in quantitative mass spectrometry to ensure analytical accuracy and reliability. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and biomedical research sectors who require precise measurement of metabolic pathways, drug metabolites, or environmental degradation products.

Application

• Mass Spectrometry Internal Standard: Serves as a critical reference compound in LC-MS and GC-MS for the accurate quantification of 2-aminobutyric acid and related metabolites in complex biological matrices.
• Pharmaceutical Research & Development: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies, drug metabolism and disposition (DMPK) analysis, and bioanalytical method development and validation.
• Metabolomics and Biomarker Discovery: Enables precise tracking and quantification in studies of metabolic disorders, cancer metabolism, and nutritional science.
• Environmental and Agrochemical Analysis: Applied as an internal standard for tracing the environmental fate, degradation, and bioaccumulation of chemical agents.
• Neuroscience Research: Utilized in studies investigating the role of amino acid neurotransmitters and neuromodulators in the central nervous system.
• Quality Control & Assurance: Provides a definitive standard for calibrating analytical instruments and validating testing protocols in GMP/GLP-compliant laboratories.

Basic Information

Product Name	Dl-2-Aminobutyric-D6 Acid
CAS No.	350820-17-6
Molecular Formula	C₄H₃D₆NO₂
Molecular Weight	121.17 g/mol (approx.)
Synonyms	2-Aminobutyric-3,3,4,4,5,5-d6 Acid; DL-2-Amino-n-butyric-d6 Acid; (±)-2-Aminobutyric-d6 Acid; 2-Amino-d6-butyric Acid; α-Aminobutyric-d6 Acid; ABA-d6; 2-AB-d6; (RS)-2-Aminobutyric-3,3,4,4,5,5-d6 Acid
EINECS	Contact for details

Quality Control

Our Dl-2-Aminobutyric-D6 Acid is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and MS, to confirm identity, chemical purity, and deuterium enrichment. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment, supporting compliance with GLP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation and maintain isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.