Description

17Beta-Dihydroequilin-16,16,17-D3 is a deuterium-labeled analog of a key equine estrogen metabolite. This compound is of significant value as a high-purity internal standard and reference material for quantitative mass spectrometry analysis. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and analytical testing facilities specializing in bioanalytical method development and steroid hormone analysis.

Application

• Primary use as an isotopically labeled internal standard for the precise quantification of endogenous estrogens and their metabolites in biological matrices via LC-MS/MS.
• Critical reference material for bioanalytical method development and validation in pharmacokinetic and pharmacodynamic studies.
• Essential component in clinical research and diagnostic assay development for hormonal profiling and endocrine disorder investigations.
• Used in veterinary pharmaceutical research, particularly in studies related to equine endocrinology and hormone replacement therapies.
• Supports quality control and impurity profiling in the synthesis of related steroid-based active pharmaceutical ingredients (APIs).
• Valuable tool for metabolomics and steroidomics research to understand metabolic pathways and biomarker discovery.

Basic Information

Product Name	17Beta-Dihydroequilin-16,16,17-D3
CAS No.	350820-03-0
Molecular Formula	C18H19D3O2
Molecular Weight	273.40 g/mol (for monoisotopic mass)
Synonyms	17β-Dihydroequilin-16,16,17-d3; [16,16,17-2H3]-17β-Dihydroequilin; Deuterated 17β-Dihydroequilin; Equilin-d3 metabolite; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-ol-16,16,17-d3; 17β-Estra-1,3,5(10),7-tetraene-3,17-diol-16,16,17-d3
EINECS	Contact for details

Quality Control

Every batch of 17Beta-Dihydroequilin-16,16,17-D3 is manufactured and analyzed under strict quality management protocols to ensure the highest standards of isotopic purity and chemical identity required for analytical applications. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific purity, isotopic enrichment, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the product label or COA. For long-term storage, consider storing desiccated at -20°C. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.