Description

L-Carnitine-D3 Hcl (Methyl-D3) is a deuterium-labeled isotopologue of L-Carnitine hydrochloride, a high-purity compound used as a critical internal standard in analytical chemistry. This stable isotope-labeled version is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses, particularly in pharmacokinetic and metabolic studies. It is primarily utilized by research institutions, pharmaceutical companies, and contract research organizations (CROs) engaged in advanced bioanalytical method development and validation.

Application

• Internal Standard for LC-MS/MS: Serves as a crucial reference compound for the precise quantification of L-Carnitine and its metabolites in complex biological matrices like plasma, serum, and urine.
• Pharmacokinetic (PK) Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) for L-Carnitine-based therapeutics.
• Metabolic Research: Used as a tracer in studies investigating fatty acid metabolism, energy production, and metabolic disorders.
• Biomarker Analysis: Facilitates the reliable measurement of L-Carnitine levels in clinical and nutritional research.
• Drug Development & Validation: A key component in developing and validating GLP/GCP-compliant bioanalytical methods for regulatory submissions.
• Quality Control in Manufacturing: Can be employed in the quality assurance of pharmaceutical products containing L-Carnitine.

Basic Information

Product Name	L-Carnitine-D3 Hcl (Methyl-D3)
CAS No.	350818-62-1
Molecular Formula	C7H12D3ClNO3
Molecular Weight	199.68 g/mol (approx.)
Synonyms	(3-Carboxy-2-hydroxypropyl)trimethylammonium-d3 chloride; L-Carnitine-d3 hydrochloride; (R)-Carnitine-d3 hydrochloride; Vitamin BT-d3 hydrochloride; Levocarnitine-d3 hydrochloride; 3-Hydroxy-4-(trimethylammonio-d3)butanoate hydrochloride; (R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium-d3 chloride
EINECS	Contact for details

Quality Control

Our L-Carnitine-D3 Hcl (Methyl-D3) is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and absence of impurities. We adhere to relevant industry standards for high-purity reference materials to ensure reliable and reproducible results in your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.