Description

1,3-Dichloroacetone-D4 is a deuterated analog of 1,3-dichloroacetone, a versatile bifunctional building block. This isotopically labeled compound is essential for advanced research and development, providing a stable, non-radioactive tracer for mechanistic studies and analytical method development. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for applications requiring precise isotopic labeling.

Application

• Pharmaceutical Research: As a deuterium-labeled intermediate in the synthesis of isotopically labeled active pharmaceutical ingredients (APIs) for metabolism, pharmacokinetic (DMPK), and bioanalytical studies.
• Analytical Chemistry: Serving as an internal standard for Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) to ensure accurate quantification of 1,3-dichloroacetone and related compounds.
• Mechanistic Studies: A critical tool for tracing reaction pathways and investigating chemical and biochemical mechanisms using deuterium as a stable isotopic label.
• Agrochemical Development: Used in the research and synthesis of novel, labeled pesticide and herbicide compounds for environmental fate and metabolic studies.
• Material Science: Potential application as a specialty monomer or cross-linking agent in the development of novel polymers with unique properties.

Basic Information

Item	Details
Product Name	1,3-Dichloroacetone-D4
CAS No.	350818-52-9
Molecular Formula	C3D4Cl2O
Molecular Weight	128.99 g/mol (approx.)
Synonyms	1,3-Dichloro-2-propanone-D4; Bis(chloromethyl) ketone-D4; D4-1,3-Dichloroacetone; Deuterated 1,3-Dichloroacetone; sym-Dichloroacetone-D4; α,α'-Dichloroacetone-D4; 1,3-Dichloroacetone-d4; [2H4]-1,3-Dichloro-2-propanone
EINECS	Contact for details

Quality Control

Our 1,3-Dichloroacetone-D4 is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high chemical and isotopic purity, critical for research integrity. A detailed Certificate of Analysis (COA) is provided, reporting key parameters such as assay by NMR or GC, isotopic enrichment (D-atom %), and impurity profile. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (GC / HPLC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.