Description

1H-Indole-1-Carboxylic Acid,2,3-Dihydro-4-Hydroxy-,1,1-Dimethylethyl Ester is a high-purity, protected indole derivative serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides with specific biological activity.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds and specialty chemicals.
• Academic & Institutional R&D: Employed in university and research institute laboratories for methodological studies and novel reaction development.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Development: Potential use in creating fluorescent probes or labeled compounds for biochemical assays.

Basic Information

Item	Details
Product Name	1H-Indole-1-Carboxylic Acid,2,3-Dihydro-4-Hydroxy-,1,1-Dimethylethyl Ester
CAS No.	350683-35-1
Molecular Formula	C14H17NO4
Molecular Weight	263.29 g/mol
Synonyms	tert-Butyl 4-hydroxy-2,3-dihydro-1H-indole-1-carboxylate; 4-Hydroxy-2,3-dihydro-1H-indole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-hydroxyindoline; 4-Hydroxyindoline-1-carboxylic acid tert-butyl ester; Boc-4-hydroxyindoline; 1-Boc-4-hydroxyindoline; 4-Hydroxy-N-Boc-indoline; 1-tert-Butoxycarbonyl-4-hydroxyindoline
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid,2,3-Dihydro-4-Hydroxy-,1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.