Description

Isoquinoline, 1,2,3,4-Tetrahydro-4-(1-Methylethyl)-, (4R)- (9Ci) is a chiral, saturated isoquinoline derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated pharmaceutical intermediate and a versatile chiral building block for constructing complex molecules with defined stereochemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Serves as a chiral scaffold or ligand in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.
• Ligand for Catalysis: Potential use in designing novel chiral catalysts for industrial-scale enantioselective transformations.

Basic Information

Product Name	Isoquinoline, 1,2,3,4-Tetrahydro-4-(1-Methylethyl)-, (4R)- (9Ci)
CAS No.	350508-61-1
Molecular Formula	C12H17N
Molecular Weight	175.27 g/mol
Synonyms	(4R)-4-Isopropyl-1,2,3,4-tetrahydroisoquinoline; (R)-4-Isopropyl-1,2,3,4-tetrahydroisoquinoline; 4-(1-Methylethyl)-1,2,3,4-tetrahydroisoquinoline, (4R)-; (R)-4-(Propan-2-yl)-1,2,3,4-tetrahydroisoquinoline; (R)-4-Isopropyl-THIQ; (R)-4-Isopropyl-1,2,3,4-tetrahydroisoquinoline; Tetrahydroisoquinoline, 4-isopropyl-, (R)-; (4R)-4-(Propan-2-yl)-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including chiral purity (enantiomeric excess) and chemical purity verification via advanced chromatographic methods. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request. Our quality system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.