Description

Ethyl (2E)-4-{2-[(3-Chloro-1-Benzothiophen-2-Yl)Carbonyl]Hydrazinyl}-4-Oxobut-2-Enoate is a high-purity, synthetic organic compound with a complex molecular structure featuring benzothiophene, hydrazine, and α,β-unsaturated ester functionalities. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used as a sophisticated scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as an intermediate in the research and production of new-generation pesticides and herbicides, leveraging its heterocyclic core.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying enzyme function and biological pathways due to its reactive hydrazine and ester groups.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic or photonic properties.

Basic Information

Product Name	Ethyl (2E)-4-{2-[(3-Chloro-1-Benzothiophen-2-Yl)Carbonyl]Hydrazinyl}-4-Oxobut-2-Enoate
CAS No.	349625-58-7
Molecular Formula	C15H13ClN2O4S
Molecular Weight	352.79 g/mol
Synonyms	Ethyl (2E)-4-[2-(3-chlorobenzo[b]thiophene-2-carbonyl)hydrazinyl]-4-oxobut-2-enoate; 2-Propenoic acid, 4-[2-[(3-chloro-1-benzothiophen-2-yl)carbonyl]hydrazinyl]-4-oxo-, ethyl ester, (2E)-; Ethyl 4-(2-(3-chlorobenzo[b]thiophene-2-carboxamido)hydrazinyl)-4-oxobut-2-enoate; 349625-58-7; (E)-Ethyl 4-(2-(3-chlorobenzo[b]thiophene-2-carboxamido)hydrazinyl)-4-oxobut-2-enoate
EINECS	Contact for details

Quality Control

Our Ethyl (2E)-4-{2-[(3-Chloro-1-Benzothiophen-2-Yl)Carbonyl]Hydrazinyl}-4-Oxobut-2-Enoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be stored away from direct light. For long-term storage, consider keeping the material under an inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.