Description

2-Chloro-3-Fluoroiodobenzene is a high-purity, multi-halogenated aromatic building block essential for advanced organic synthesis. Its unique combination of chlorine, fluorine, and iodine substituents on the benzene ring makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides where the introduction of halogenated aromatic rings is required for bioactivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Reagent: Facilitates various functional group transformations and serves as a scaffold for further derivatization in academic and industrial research.

Basic Information

Product Name	2-Chloro-3-Fluoroiodobenzene
CAS No.	348642-49-9
Molecular Formula	C6H3ClFI
Molecular Weight	256.44 g/mol
Synonyms	1-Chloro-2-fluoro-3-iodobenzene; 3-Fluoro-2-chloro-1-iodobenzene; 2-Chloro-3-fluoro-1-iodobenzene; Benzene, 2-chloro-3-fluoro-1-iodo-; (2-Chloro-3-fluorophenyl)iodide; 2-Chloro-3-fluorophenyl iodide; 1-Iodo-2-chloro-3-fluorobenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluoroiodobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and our quality protocols are designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. The container should be kept tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.