Description

2H-Benzimidazol-2-One,6-Fluoro-1,3-Dihydro-1-Methyl-(9Ci) is a high-purity fluorinated benzimidazole derivative, a crucial advanced pharmaceutical intermediate for modern drug discovery and development. Its value lies in its role as a key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular scaffolds. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop new fluorinated compounds with enhanced biological activity and metabolic stability. The CAS number for this product is 348133-45-9.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in oncology, antiviral, and central nervous system (CNS) drug research.
• Agrochemical Research: Used in developing new-generation pesticides and herbicides, where the fluorinated benzimidazole core can contribute to improved efficacy and selectivity.
• Organic Synthesis & Chemical Research: Serves as a versatile precursor for creating complex heterocyclic compounds in academic and industrial R&D laboratories.
• Material Science: Potential application in the synthesis of specialty polymers and advanced organic materials requiring specific fluorinated motifs.
• Bioconjugation & Probe Development: Can be utilized in the creation of fluorescent probes or biochemical tools for diagnostic and life science research applications.

Basic Information

Product Name	2H-Benzimidazol-2-One,6-Fluoro-1,3-Dihydro-1-Methyl-(9Ci)
CAS No.	348133-45-9
Molecular Formula	C8H7FN2O
Molecular Weight	166.15 g/mol
Synonyms	6-Fluoro-1-methyl-1,3-dihydro-2H-benzimidazol-2-one; 6-Fluoro-1-methyl-2-benzimidazolinone; 1-Methyl-6-fluoro-2-benzimidazolinone; 348133-45-9; 6-Fluoro-1-methylbenzimidazol-2(3H)-one; 6-Fluoro-1-methyl-1H-benzo[d]imidazol-2(3H)-one; 1-Methyl-6-fluoro-1,3-dihydro-2H-benzimidazol-2-one
EINECS	Contact for details

Quality Control

Our 2H-Benzimidazol-2-One,6-Fluoro-1,3-Dihydro-1-Methyl-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.