Description

Carbamic Acid, n-[4-(Chlorocarbonyl)-2-Thiazolyl]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific thiazole and carbamate functional groups. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug molecules, particularly those targeting specific biological pathways.
• API Synthesis: Used as a building block for constructing the core scaffold or side chains of potential new Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Enables the exploration of structure-activity relationships (SAR) in drug discovery programs within academic and industrial R&D labs.
• Process Development: Serves as a standard or starting material for optimizing scalable and efficient manufacturing routes for target compounds.
• Bioconjugation & Probe Development: The reactive chlorocarbonyl group allows for conjugation to biomolecules, useful in creating diagnostic probes or targeted drug delivery systems.

Basic Information

Product Name	Carbamic Acid, n-[4-(Chlorocarbonyl)-2-Thiazolyl]-, 1,1-Dimethylethyl Ester
CAS No.	347869-17-4
Molecular Formula	C9H11ClN2O3S
Molecular Weight	262.71 g/mol
Synonyms	tert-Butyl N-[4-(chlorocarbonyl)-1,3-thiazol-2-yl]carbamate; 2-[(tert-Butoxycarbonyl)amino]-1,3-thiazole-4-carbonyl chloride; Boc-2-Amino-4-thiazolecarbonyl chloride; (2-((tert-Butoxycarbonyl)amino)thiazole-4-carbonyl) chloride; 4-(Chloroformyl)-2-[[(1,1-dimethylethoxy)carbonyl]amino]thiazole; 2-(Boc-amino)-4-thiazolecarbonyl chloride; N-Boc-2-amino-4-thiazolecarbonyl chloride
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, n-[4-(Chlorocarbonyl)-2-Thiazolyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.