Description

2,3-Butane-D8-Diol is a deuterium-labeled isotopologue of 2,3-butanediol, a valuable four-carbon diol. This compound is essential as a stable isotope-labeled internal standard for precise quantitative analysis in mass spectrometry and nuclear magnetic resonance (NMR) studies. It is primarily needed by research institutions, pharmaceutical companies, and analytical laboratories engaged in metabolic pathway tracing, pharmacokinetic research, and the development of deuterated active pharmaceutical ingredients (APIs).

Application

• Internal Standard for Analytical Chemistry: Used in GC-MS, LC-MS, and NMR for the accurate quantification of 2,3-butanediol and related metabolites in complex biological matrices.
• Metabolic Pathway Research: A critical tracer for studying biochemical pathways in microbiology, plant physiology, and mammalian systems.
• Pharmaceutical R&D: Employed in the synthesis and analysis of deuterated drug candidates to enhance metabolic stability and for conducting absorption, distribution, metabolism, and excretion (ADME) studies.
• Deuterated Solvent & Reagent: Serves as a building block or solvent in specialized synthetic chemistry requiring deuterium incorporation.
• Quality Control & Reference Material: Acts as a certified reference material (CRM) for calibrating analytical instruments and validating methods in quality control laboratories.

Basic Information

Product Name	2,3-Butane-D8-Diol
CAS No.	347841-77-4
Molecular Formula	C4D8O2
Molecular Weight	96.17 g/mol
Synonyms	(2R,3R)-2,3-Butanediol-d8; (2S,3S)-2,3-Butanediol-d8; meso-2,3-Butanediol-d8; 2,3-Dideuteriooxybutane-d6; Butane-2,3-diol-d8; 2,3-Dihydroxybutane-d8; Deuterated 2,3-Butanediol; 2,3-Butylene glycol-d8
EINECS	Contact for details

Quality Control

Our 2,3-Butane-D8-Diol is manufactured under strict quality management systems to ensure high isotopic and chemical purity, critical for research accuracy. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity, and specific analytical results. We adhere to relevant standards for high-purity reference materials to guarantee reliable and reproducible performance in your sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (D-atom %)	≥ 98%
Chemical Purity (GC / HPLC)	≥ 98%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.