Description

Bis(2-Chloroethoxy)Ethane-D12 is a deuterated analog of bis(2-chloroethoxy)ethane, a specialized chemical building block where hydrogen atoms are replaced with deuterium, a stable isotope. This deuteration is critical for applications requiring enhanced molecular stability, reduced metabolic interference, or specific spectroscopic properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for use as an internal standard, a labeled precursor in synthesis, or a probe in mechanistic studies.

Application

• Deuterated Internal Standard: Used in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) analysis for accurate measurement of its non-deuterated counterpart in complex matrices.
• Pharmaceutical Research: Serves as a stable isotope-labeled intermediate in the synthesis of deuterated drug candidates for pharmacokinetic and metabolic stability studies.
• Agrochemical Development: Employed in the creation of labeled pesticides or herbicides to study environmental fate, degradation pathways, and residue analysis.
• Polymer & Materials Science: Acts as a chain extender or cross-linking agent in the development of specialized polymers, where deuterium labeling aids in structural analysis using neutron scattering techniques.
• Mechanistic Probes: Utilized in chemical and biochemical research to trace reaction pathways and investigate mechanisms due to the kinetic isotope effect (KIE).
• Analytical Reference Material: Provides a high-purity reference compound for calibrating analytical instruments and validating methods in regulatory testing environments.

Basic Information

Product Name	Bis(2-Chloroethoxy)Ethane-D12
CAS No.	347841-75-2
Molecular Formula	C6D12Cl2O2
Molecular Weight	Contact for details
Synonyms	1,2-Bis(2-chloroethoxy)ethane-d12; Ethane-d12, 1,2-bis(2-chloroethoxy)-; Dichloroethyl Ether-d12; D12-Bis(2-chloroethyl) Ether; Deuterated 1,5-Dichloro-3-oxapentane; [D12]-1,2-Bis(2-chloroethoxy)ethane; Bis(β-chloroethyl) Ether-d12; Labeled Dichloroethyl Ether
EINECS	Contact for details

Quality Control

Every batch of Bis(2-Chloroethoxy)Ethane-D12 is produced and analyzed under strict quality management protocols to ensure isotopic purity, chemical purity, and batch-to-batch consistency. Our quality assurance includes comprehensive testing via NMR, MS, and HPLC to confirm deuterium incorporation and impurity profiles. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and specific tests are provided and can be tailored to meet the requirements of cGMP, ISO, or other relevant regulatory frameworks for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under optimal conditions, please contact our technical service team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 97%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.