Description

1-[4-(1,1-Dioxido-1,2-Benzisothiazol-3-Yl)Piperazin-1-Yl]Propan-2-Ol is a high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound is valued for its unique benzisothiazole dioxide and piperazine-based structure, which serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the discovery and process development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and anti-infective research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological pathways.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists to explore new structure-activity relationships (SAR).
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for potential active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Tool Compound: Utilized in biochemical assays to study specific enzyme interactions or receptor binding.

Basic Information

Product Name	1-[4-(1,1-Dioxido-1,2-Benzisothiazol-3-Yl)Piperazin-1-Yl]Propan-2-Ol
CAS No.	346448-88-2
Molecular Formula	C14H19N3O3S
Molecular Weight	309.38 g/mol
Synonyms	2-Propanol, 1-[4-(1,1-dioxido-1,2-benzisothiazol-3-yl)-1-piperazinyl]-; 3-(4-(2-Hydroxypropyl)piperazin-1-yl)-1,2-benzisothiazole 1,1-dioxide; 1,2-Benzisothiazole, 3-[4-(2-hydroxypropyl)-1-piperazinyl]-, 1,1-dioxide; 346448-88-2; 1-(4-(1,1-Dioxido-1,2-benzisothiazol-3-yl)piperazin-1-yl)propan-2-ol
EINECS	Contact for details

Quality Control

Our 1-[4-(1,1-Dioxido-1,2-Benzisothiazol-3-Yl)Piperazin-1-Yl]Propan-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.