Description

1-({3-Nitrophenyl}Methyl)-1H-Indole-2,3-Dione CAS NO 346442-46-4 is a specialized organic compound belonging to the isatin derivative family, characterized by a nitrobenzyl substitution. This molecular architecture makes it a valuable advanced pharmaceutical intermediate (API intermediate) and a versatile building block for complex organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active compounds. Its defined structure and high purity are critical for ensuring reproducibility and efficacy in downstream applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting neurological or anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators due to its bioactive indole core.
• Organic Synthesis Building Block: Employed in heterocyclic and medicinal chemistry for constructing complex molecules via reactions at the isatin carbonyl groups or the aromatic nitro group.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers or organic electronic materials.
• Biochemical Tool Compound: Potentially used in biochemical assays and as a probe for studying enzyme inhibition or specific biological mechanisms.

Basic Information

Product Name	1-({3-Nitrophenyl}Methyl)-1H-Indole-2,3-Dione
CAS No.	346442-46-4
Molecular Formula	C15H10N2O4
Molecular Weight	282.25 g/mol
Synonyms	1-[(3-Nitrophenyl)methyl]indole-2,3-dione; 1-(3-Nitrobenzyl)isatin; 3-Nitrobenzylisatin; 1H-Indole-2,3-dione, 1-[(3-nitrophenyl)methyl]-; Isatin, 1-(3-nitrobenzyl)-; N-(3-Nitrobenzyl)isatin
EINECS	Contact for details

Quality Control

Our production of 1-({3-Nitrophenyl}Methyl)-1H-Indole-2,3-Dione adheres to stringent in-process controls and final batch analysis to ensure high purity and consistency. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.