Description

5-(Aminocarbonyl)Thiophene-2-Carboxylic Acid is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel thiophene-based molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides that leverage the thiophene moiety for enhanced biological activity.
• Material Science Research: Serves as a precursor for functionalized polymers and organic electronic materials due to its conjugated thiophene core and reactive carboxylic acid group.
• Chemical Biology: Employed as a building block for designing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	5-(Aminocarbonyl)Thiophene-2-Carboxylic Acid
CAS No.	345992-88-3
Molecular Formula	C6H5NO3S
Molecular Weight	171.17 g/mol
Synonyms	5-Carbamoylthiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-carbamoyl-; 5-Carbamoyl-2-thiophenecarboxylic acid; Thiophene-2,5-dicarboxamide (misnomer, but common); T2A-5CA; 5-Aminocarbonylthiophene-2-carboxylic Acid; 2-Carboxy-5-thiophenecarboxamide
EINECS	Contact for details

Quality Control

Our 5-(Aminocarbonyl)Thiophene-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.