Description

1-(2,3,4-Trimethoxyphenyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid is a complex, multi-functional heterocyclic compound belonging to the β-carboline alkaloid class. This molecule is of significant interest in advanced organic synthesis and pharmaceutical research due to its intricate structure, which combines a tetrahydro-β-carboline core with a trimethoxyphenyl substituent. It serves as a critical pharmaceutical intermediate and a valuable scaffold for medicinal chemistry programs. Target users include research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new β-carboline-based bioactive molecules.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Employed in advanced synthetic routes to create libraries of novel heterocyclic compounds for screening.
• Biochemical Research: Investigated for its potential interactions with various enzymes and receptors due to the pharmacologically privileged β-carboline structure.

Basic Information

Product Name	1-(2,3,4-Trimethoxyphenyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic Acid
CAS No.	345637-82-3
Molecular Formula	C21H22N2O5
Molecular Weight	382.41 g/mol
Synonyms	1-(2,3,4-Trimethoxyphenyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic Acid; 1-(2,3,4-Trimethoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid; 3-Carboxy-1-(2,3,4-trimethoxyphenyl)-1,2,3,4-tetrahydro-β-carboline; β-Carboline-3-carboxylic acid, 1,2,3,4-tetrahydro-1-(2,3,4-trimethoxyphenyl)-; 345637-82-3
EINECS	Contact for details

Quality Control

Our production of 1-(2,3,4-Trimethoxyphenyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality systems are designed to support cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.