Description

1H-Indole, 5-Bromo-4-Fluoro- is a high-purity halogenated indole derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, enabling precise structural modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Used in the research and development of organic electronic materials, such as OLEDs and conductive polymers, due to the indole core's electronic properties.
• Biochemical Probe Synthesis: Employed in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and contract research organizations (CROs) exploring new heterocyclic compounds.

Basic Information

Product Name	1H-Indole, 5-Bromo-4-Fluoro-
CAS No.	344790-96-1
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	5-Bromo-4-fluoro-1H-indole; 4-Fluoro-5-bromoindole; 5-Bromo-4-fluoroindole; 1H-Indole, 5-bromo-4-fluoro-; 344790-96-1; 4-Fluoro-5-bromo-1H-indole; 5-Bromo-4-fluoro-1H-indole
EINECS	Contact for details

Quality Control

Our 1H-Indole, 5-Bromo-4-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.