Description

8-Indolizinecarboxylic Acid, 2,3,5,6,7,8-Hexahydro-5-Thioxo-, Ethyl Ester is a specialized heterocyclic building block featuring a fused indolizine core with a thioxo and ester functional group. This compound is valued for its unique molecular architecture, making it a critical intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules and exploring novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic pharmacophores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its heterocyclic structure can contribute to unique modes of action.
• Fine Chemical Synthesis: Acts as a versatile building block for creating complex organic molecules used in material science, dyes, and specialty chemicals.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies in heterocyclic chemistry and the exploration of new synthetic pathways.
• Ligand & Catalyst Development: Potential use in designing novel ligands for metal catalysis due to the presence of sulfur and nitrogen donor atoms within its structure.

Basic Information

Item	Details
Product Name	8-Indolizinecarboxylic Acid, 2,3,5,6,7,8-Hexahydro-5-Thioxo-, Ethyl Ester
CAS No.	344335-03-1
Molecular Formula	C11H15NO2S
Molecular Weight	225.31 g/mol
Synonyms	Ethyl 5-thioxo-2,3,5,6,7,8-hexahydro-8-indolizinecarboxylate; 2,3,5,6,7,8-Hexahydro-5-thioxo-8-indolizinecarboxylic acid ethyl ester; 5-Thioxo-2,3,5,6,7,8-hexahydroindolizine-8-carboxylic acid ethyl ester; 8-Carbethoxy-2,3,5,6,7,8-hexahydro-5-thioxoindolizine; Ethyl 2,3,5,6,7,8-hexahydro-5-thioxoindolizine-8-carboxylate
EINECS	Contact for details

Quality Control

Our production of 8-Indolizinecarboxylic Acid, 2,3,5,6,7,8-Hexahydro-5-Thioxo-, Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.